| Parameter | Prokaryotic Cell | Eukaryotic Cell |
| Nucleus | Absent | Present |
| Cell Type | Usually unicellular | Usually multicellular |
| True Membrane | Absent | Present |
| Cell size | 1-10μm | 10-100μm |
| Endoplasmic reticulum | Absent | Present |
| Mitochondria | Absent | Present |
| Cytoskeleton | Absent | Present |
| DNA wrapping on proteins | Multiple proteins act together to fold and condense prokaryotic DNA | Eukaryotes wrap their DNA around proteins called his-tones. |
| Ribosomes | Smaller | Larger |
| Golgi apparatus | Absent | Present |
| Choroplasts | Absent | Present |
| Cell Wall | Usually chemically complexed | Only in plant cells and fungi |
| Example | Bacteria and Archaea | Animals and Plants |